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9, pp. J. (2009) Fate of aflatoxinM1 during Manufacture and Storage of Feta Cheese. Toxicology and Chemical Food Safety Vol 74, No. 5, pp. ; Centonze, D. (2007) Validation according to European Commission Decision 2002/657/EC of a confirmatory method for aflatoxin M1 in milk based on immunoaffinity columns and high performance liquid chromatography with fluorescence detection. Analytica Chimica Acta Vol. 594, No. 2 (July 2007), pp. M. (2011) Survey of aflatoxin M1 in cheese from the North-east region of Sao Paulo, Brazil.
It is widely accepted that aflatoxin contamination in the region is correlated well with the onset of liver cancer in human. Studies showed that AFB1 causes the p53 gene mutation in human cancer cell. P53 is a tumor suppressor, a transcription factor involved in the regulation of the cell cycle. 1 Carcinogenecity Aflatoxins are the most notorious within mycotoxins. These toxins target liver of human and animal and can lead to hepatic cancer and even death. Among them, the AFB1 was categorized as No.
Ji, R. & Li, Y. (2007). Pollution Survey of Aflatoxin B1 in Grain, Oils and Food on Beijing City, Journal of Hygiene Research 36, 237-239. Gao, Y. & Ding, W. (2010). , Microbiology 37, 369-374. , Jiang, L. & Zhang, Y. (2004). Hazard of Aflatoxin in Food and Its Methods for Removing, Food Research and Developent 25, 120-123. Hu, N. & Xu, Y. (2009). Research on the Application of Differentially Expressed Genes Related Analysis in the Process of Aflatoxin Biosynthesis, Food Science 30, 208-211. Huang, T.